658 research outputs found
Transvaginal endoscopy and small ovarian endometriomas: unravelling the missing link?
The incidence of endometriosis in the infertile female is estimated to be between 20 and 50 %. Although the causal relationship between endometriosis and infertility has not been proven, it is generally accepted that the disease impairs reproductive outcome. Indirect imaging techniques and transvaginal laparoscopy now offer the possibility of an early stage diagnosis. Although it remains debated whether the disease is progressive, treatment in an early stage is recommendable as it carries less risk for ovarian damage, hence premature ovarian failure. Under water, inspection with the technique of transvaginal hydrolaparoscopy (THL) accurately shows the invagination of the ovarian cortex as minimal superficial lesions but with the presence of well-differentiated endometrial like tissue at the base, the lateral walls and especially the inner edges of the small endometrioma. An inflammatory environment is responsible for the formation of connecting adhesions with the broad ligament and lateral wall with invasion of endometrial-like tissue and formation of adenomyotic lesions. In around 50 % of the small endometriomas, adhesiolysis is necessary at the site of invagination with opening of the cyst, to free the chocolate content and hereby recognize the underlying endometrioma. The detailed inspection of these early-stage endometriotic lesions at THL reunites the hypothesis of Sampson with the observation of Hughesdon
Low-speed impact craters in loose granular media
We report on craters formed by balls dropped into dry, non-cohesive, granular
media. By explicit variation of ball density , diameter , and
drop height , the crater diameter is confirmed to scale as the 1/4 power of
the energy of the ball at impact:
. Against expectation, a different
scaling law is discovered for the crater depth:
. The scaling with properties of
the medium is also established. The crater depth has significance for granular
mechanics in that it relates to the stopping force on the ball.Comment: experiment; 4 pages, 3 figure
Vacuum properties of nonsymmetric gravity in de Sitter space
We consider quantum effects of a massive antisymmetric tensor field on the
dynamics of de Sitter space-time. Our starting point is the most general,
stable, linearized Lagrangian arising in nonsymmetric gravitational theories
(NGTs), where part of the antisymmetric field mass is generated by the
cosmological term. We construct a renormalization group (RG) improved effective
action by integrating out one loop vacuum fluctuations of the antisymmetric
tensor field and show that, in the limit when the RG scale goes to zero, the
Hubble parameter -- and thus the effective cosmological constant -- relaxes
rapidly to zero. We thus conclude that quantum loop effects in de Sitter space
can dramatically change the infrared sector of the on-shell gravity, making the
expansion rate insensitive to the original (bare) cosmological constant.Comment: 32 pages, 2 eps figure
Towards a Theoretical Framework for Understanding the Development of Media Related Needs
The question of why people select and prefer particular media activities has led to the development of a number of ‘needs’ approaches to media use. Whilst some frameworks have been developed within the context of media use (e.g. uses and gratifications), others (e.g. Tamborini et al, 2011) look to combine general theories of basic human needs, such as Self-Determination Theory (Deci &Ryan, 1985) with hedonic gratifications. Drawing on these approaches, a framework is proposed that maps findings from children’s and adolescents’ media use to four basic human needs: competence, autonomy, relatedness and hedonic needs. The current paper argues that a basic needs approach is useful for understanding how media-related needs emerge and are expressed through development
Spherical collapse of dark energy with an arbitrary sound speed
We consider a generic type of dark energy fluid, characterised by a constant
equation of state parameter w and sound speed c_s, and investigate the impact
of dark energy clustering on cosmic structure formation using the spherical
collapse model. Along the way, we also discuss in detail the evolution of dark
energy perturbations in the linear regime. We find that the introduction of a
finite sound speed into the picture necessarily induces a scale-dependence in
the dark energy clustering, which in turn affects the dynamics of the spherical
collapse in a scale-dependent way. As with other, more conventional fluids, we
can define a Jeans scale for the dark energy clustering, and hence a Jeans mass
M_J for the dark matter which feels the effect of dark energy clustering via
gravitational interactions. For bound objects (halos) with masses M >> M_J, the
effect of dark energy clustering is maximal. For those with M << M_J, the dark
energy component is effectively homogeneous, and its role in the formation of
these structures is reduced to its effects on the Hubble expansion rate. To
compute quantitatively the virial density and the linearly extrapolated
threshold density, we use a quasi-linear approach which is expected to be valid
up to around the Jeans mass. We find an interesting dependence of these
quantities on the halo mass M, given some w and c_s. The dependence is the
strongest for masses lying in the vicinity of M ~ M_J. Observing this
M-dependence will be a tell-tale sign that dark energy is dynamic, and a great
leap towards pinning down its clustering properties.Comment: 25 pages, 6 figures, matches version published in JCA
Testing the Void against Cosmological data: fitting CMB, BAO, SN and H0
In this paper, instead of invoking Dark Energy, we try and fit various
cosmological observations with a large Gpc scale under-dense region (Void)
which is modeled by a Lemaitre-Tolman-Bondi metric that at large distances
becomes a homogeneous FLRW metric. We improve on previous analyses by allowing
for nonzero overall curvature, accurately computing the distance to the
last-scattering surface and the observed scale of the Baryon Acoustic peaks,
and investigating important effects that could arise from having nontrivial
Void density profiles. We mainly focus on the WMAP 7-yr data (TT and TE),
Supernova data (SDSS SN), Hubble constant measurements (HST) and Baryon
Acoustic Oscillation data (SDSS and LRG). We find that the inclusion of a
nonzero overall curvature drastically improves the goodness of fit of the Void
model, bringing it very close to that of a homogeneous universe containing Dark
Energy, while by varying the profile one can increase the value of the local
Hubble parameter which has been a challenge for these models. We also try to
gauge how well our model can fit the large-scale-structure data, but a
comprehensive analysis will require the knowledge of perturbations on LTB
metrics. The model is consistent with the CMB dipole if the observer is about
15 Mpc off the centre of the Void. Remarkably, such an off-center position may
be able to account for the recent anomalous measurements of a large bulk flow
from kSZ data. Finally we provide several analytical approximations in
different regimes for the LTB metric, and a numerical module for CosmoMC, thus
allowing for a MCMC exploration of the full parameter space.Comment: 70 pages, 12 figures, matches version accepted for publication in
JCAP. References added, numerical values in tables changed due to minor bug,
conclusions unaltered. Numerical module available at
http://web.physik.rwth-aachen.de/download/valkenburg
Constraining Inflation
Slow roll reconstruction is derived from the Hamilton-Jacobi formulation of
inflationary dynamics. It automatically includes information from sub-leading
terms in slow roll, and facilitatesthe inclusion of priors based on the
duration on inflation. We show that at low inflationary scales the
Hamilton-Jacobi equations simplify considerably. We provide a new
classification scheme for inflationary models, based solely on the number of
parameters needed to specify the potential, and provide forecasts for likely
bounds on the slow roll parameters from future datasets. A minimal running of
the spectral index, induced solely by the first two slow roll parameters
(\epsilon and \eta) appears to be effectively undetectable by realistic Cosmic
Microwave Background experiments. However, we show that the ability to detect
this signal increases with the lever arm in comoving wavenumber, and we
conjecture that high redshift 21 cm data may allow tests of second order
consistency conditions on inflation. Finally, we point out that the second
order corrections to the spectral index are correlated with the inflationary
scale, and thus the amplitude of the CMB B-mode.Comment: 32 pages. v
Utility of Parental Mediation Model on Youth’s Problematic Online Gaming
The Parental Mediation Model PMM) was initially designed to regulate children’s attitudes towards the traditional media. In the present era, because of prevalent online media there is a need for similar regulative measures. Spending long hours on social media and playing online games increase the risks of exposure to the negative outcomes of online gaming. This paper initially applied the PMM developed by European Kids Online to (i) test the reliability and validity of this model and (ii) identify the effectiveness of this model in controlling problematic online gaming (POG). The data were collected from 592 participants comprising 296 parents and 296 students of four foreign universities, aged 16 to 22 years in Kuala Lumpur (Malaysia). The study found that the modified model of the five-factor PMM (Technical mediation, Monitoring mediation, Restrictive mediation, Active Mediation of Internet Safety, and Active mediation of Internet Use) functions as a predictor for mitigating POG. The findings suggest the existence of a positive relation between ‘monitoring’ and ‘restrictive’ mediation strategies and exposure to POG while Active Mediation of Internet Safety and Active mediation of Internet use were insignificant predictors. Results showed a higher utility of ‘technical’ strategies by the parents led to less POG. The findings of this study do not support the literature suggesting active mediation is more effective for reducing youth’s risky behaviour. Instead, parents need to apply more technical mediations with their children and adolescents’ Internet use to minimize the negative effects of online gaming
Covariant coarse-graining of inhomogeneous dust flow in General Relativity
A new definition of coarse-grained quantities describing the dust flow in
General Relativity is proposed. It assigns the coarse--grained expansion, shear
and vorticity to finite-size comoving domains of fluid in a covariant,
coordinate-independent manner. The coarse--grained quantities are all
quasi-local functionals, depending only on the geometry of the boundary of the
considered domain. They can be thought of as relativistic generalizations of
simple volume averages of local quantities in a flat space. The procedure is
based on the isometric embedding theorem for S^2 surfaces and thus requires the
boundary of the domain in question to have spherical topology and positive
scalar curvature. We prove that in the limit of infinitesimally small volume
the proposed quantities reproduce the local expansion, shear and vorticity. In
case of irrotational flow we derive the time evolution for the coarse-grained
quantities and show that its structure is very similar to the evolution
equation for their local counterparts. Additional terms appearing in it may
serve as a measure of the backreacton of small-scale inhomogeneities of the
flow on the large-scale motion of the fluid inside the domain and therefore the
result may be interesting in the context of the cosmological backreaction
problem. We also consider the application of the proposed coarse-graining
procedure to a number of known exact solutions of Einstein equations with dust
and show that it yields reasonable results.Comment: 17 pages, 5 figures. Version accepted in Classical and Quantum
Gravity
Primordial Black Holes, Eternal Inflation, and the Inflationary Parameter Space after WMAP5
We consider constraints on inflation driven by a single, minimally coupled
scalar field in the light of the WMAP5 dataset, as well as ACBAR and the
SuperNova Legacy Survey. We use the Slow Roll Reconstruction algorithm to
derive optimal constraints on the inflationary parameter space. The scale
dependence in the slope of the scalar spectrum permitted by WMAP5 is large
enough to lead to viable models where the small scale perturbations have a
substantial amplitude when extrapolated to the end of inflation. We find that
excluding parameter values which would cause the overproduction of primordial
black holes or even the onset of eternal inflation leads to potentially
significant constraints on the slow roll parameters. Finally, we present a more
sophisticated approach to including priors based on the total duration of
inflation, and discuss the resulting restrictions on the inflationary parameter
space.Comment: v2: version published in JCAP. Minor clarifications and references
adde
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